The short version
- 1
TSH is the main number, and it works in reverse: high TSH usually means an underactive thyroid, low TSH an overactive one.8
- 2
A mildly high TSH with a normal T4 is worth repeating in 2–3 months: more than half of people with 5.5–10 were normal on retest.20,22
- 3
There’s no special “thyroid diet”. Cooked cabbage, soy and millets are fine; use iodised salt.6,24,26,28
Your number
Where does your TSH sit?
Slide the dot to the TSH on your report.
Your report
Read TSH together with T4
- High TSH, low free T4
- An underactive thyroid (primary hypothyroidism).
- High TSH, normal free T4
- Subclinical: mild or early. Repeat the test before acting on it.
- Low TSH, high free T4
- An overactive thyroid (hyperthyroidism).
- Low TSH, normal T4, high T3
- Some overactive thyroids show only a high T3.
- Low TSH, low free T4
- A problem in the pituitary gland, not the thyroid (secondary hypothyroidism).
TSH is the best first test. Free T4 is more reliable than total T4 in pregnancy or on the pill, and T3 rarely helps with an underactive thyroid. Free T4 usually runs about 0.8–1.9 ng/dL (10.3–24.5 pmol/L).8,14,15,20
India
One in ten, and many don’t know
- 1 in 10
- adults in eight Indian cities had an underactive thyroid, and about a third of them didn’t know it.1
- 15.9%
- of women had it, against 5.0% of men.1
- 21.9%
- tested positive for anti-TPO antibodies.1
Pooled studies project about 42 million Indians with thyroid disease. Healthy Delhi adults averaged a TSH of 2.2.2,3
Borderline?
Retest before you’re labelled
How often a raised TSH was normal on the next test, among 346,549 people not on thyroid medicine.
- First TSH 5.5–1062% normal on retest
- First TSH above 1027% normal on retest
The European Thyroid Association advises repeating TSH, free T4 and anti-TPO after 2–3 months. A 2019 BMJ guideline, drawing on 21 trials, recommends against thyroid hormone for most adults with subclinical hypothyroidism: it didn’t help tiredness, mood, quality of life or weight. It doesn’t cover women trying to conceive or a TSH above 20. Never stop or change a medicine without your doctor.20,21
Testing
Getting a reliable result
2 days before
Pause biotin
Biotin supplements can throw the result off.8
The day
Test in the morning
TSH runs highest early in the day and can swing by about 1–2 mIU/L across it.13,19
After an illness
Wait a few weeks
TSH can dip during an illness and rise as you recover.19
Every repeat
Same lab if you can
Ranges differ between labs and machines. Once on treatment, doctors usually recheck 6–8 weeks after any change.19,20
Pregnancy
If you’re pregnant or planning to be
TSH ranges change in each trimester, and Indian sources don’t agree.
- First trimester
- MoHFW 2014: 0.1–2.5. Healthy pregnant women in Delhi: 0.6–5.0.
- Second trimester
- MoHFW 2014: 0.2–3. Delhi study: 0.44–5.78.
- Third trimester
- MoHFW 2014: 0.3–3. Delhi study: 0.74–5.7.
That’s why your doctor uses trimester-specific ranges. Indian studies find an underactive thyroid in 4.8–12% of pregnancies. Already on thyroid medicine? Get your TSH checked as soon as the pregnancy is confirmed.4,5,12
Food and weight
What you might hear
They say
“Never eat cabbage or cauliflower with a thyroid problem.”
They say
“Soy is banned.”
Actually
Fourteen trials found little or no effect on thyroid function when iodine intake is adequate. Soy may change how much medicine you need, so tell your doctor, but you don’t have to avoid it.24
They say
“Everyone with Hashimoto’s must go gluten-free.”
Actually
A meta-analysis found the evidence isn’t enough to recommend it for everyone.25
They say
“Millets cause goitre.”
They say
“Thyroid tablets will make me thin.”
They say
“Positive anti-TPO means I need medicine now.”
Losing weight with a thyroid condition follows the usual rules: ICMR-NIN advises about 0.5 kg a week, never below 1,000 calories a day, and no crash diets. Keep using iodised salt; 94.3% of Indian homes already do. Our Indian weight-loss plan works the same way.6,7
See a doctor soon if
- You’re pregnant or planning a pregnancy, and any thyroid result is off.
- An older person with an underactive thyroid becomes very drowsy, cold or confused. This is a rare emergency.
- A swelling in your neck makes it hard to breathe, or you wheeze: get emergency care. Trouble swallowing or a hoarse voice also needs a doctor.
- Your TSH is above 10, or your free T4 is low.
- On treatment, you feel nervous or hot, your heart races, or you lose weight without trying.
Don’t start, stop or change thyroid tablets without your doctor.
Warning signs from the American Thyroid Association, the NHS and the European Thyroid Association.1,5,9,12,17,18,20



